The Fountain Of Youth: Do Retinol Products Really Get Rid Of Wrinkles?

Updated 3/26/21Retinol is a clinically proven vitamin A ingredient that offers a number of skin benefits. It stimulates cell regeneration, boosts the production of collagen, promotes skin elasticity, and offers firming, brightening, and smoothing effects. It’s a true multi-tasking skincare ingredient, which is why I formulated my Advanced Resurfacing Serum with it. With continued use, I know that this serum can literally transform the look of your skin by reversing the visual effects of sun damage, softening lines and wrinkles, fading brown spots, and smoothing texture. This product has been in the making for a long, long time, and there’s a whole back story to how it came to be. Let me share it with you.

Watch: Retinol for Sensitive Skin

The Retin-A Back Story: 

I saw very early on in my esthetics career how the prescription form of vitamin A, which is called Retin-A, could reverse the signs of aging. It was the late ’80s, and I was living in Boston as a fresh graduate of the Catherine Hinds School of Esthetics. As a young, 18-year-old esthetician, I couldn’t wait to get my career started. I got my first job at a full service salon, which offered skin treatments along with hair and nail services.

One of the salon’s regular clients was a man named Dr. Thomas Fitzpatrick, who, at the time, was the Chief of Dermatology at Mass General Hospital (for any estheticians reading this, he was the inventor of the Fitzpatrick Skin Type testing). When he would come in for his haircut appointments, he would make conversation with the estheticians since we were all in the skincare industry. Because he was such a prestigious dermatologist, I was always asking him questions about skin and hanging on to every word he said…

I’ll never forget the day he showed me his hands. He held out both of his hands and said, “Renée, can you see the difference in my hands?” I looked and couldn’t believe my eyes. One hand looked so much younger than the other; it had less wrinkles, less brown spots, and less uneven texture. This was a man who was in his mid-60’s, so his hands were showing the effects of aging, but one was much more prominently aged than the other.

How did he get one hand to look so much younger than the other?

The answer is prescription Retin-A. For many years, Retin-A was a topical cream used exclusively to treat acne. Since it had harsh side effects, such as dryness, redness, and peeling, a doctor would need to give very specific instructions to their acne patients about how much to use to lessen these negative effects. Dr. Fitzpatrick would always demonstrate by taking a pea-size amount (which was his recommended amount for the entire face) and rubbing it on ONE of his hands. He would do this, day in and day out. To his surprise, he began to notice that one hand looked much younger than the other! This realization was what led Dr. Fitzpatrick to become one of the doctors instrumental in getting the FDA to recognize Retin-A as a cream that could help reduce wrinkles.

In 1991, even though it hadn’t received FDA approval for treating wrinkles yet (this would happen in 1995), word got out about this “fountain of youth.” Soon, Retin-A was all the rage, and women were lining up at their dermatologists’ offices. However, the use of Retin-A didn’t go so well at first. There wasn’t enough awareness about how to use it properly to lessen the drying side effects, so women were slathering it on. They soon discovered the downside of trying to achieve younger-looking skin; peeling, flaking, dryness, redness and overall irritation set in quickly.

I remember the initial popularity of Retin-A so vividly, because my appointment schedule filled up with clients coming to see me to address their dryness. They would come in and say, “I need your help, Renée. I’m using this new prescription, and my skin is a mess!” I even had a client whose skin was so dry that when she smiled her skin cracked and she began to bleed in front of me. To treat my clients with extreme dryness, I would give them moisturizing and rehydrating facials, but within a few days the moisture would evaporate and dryness would set right back in again so long as they continued to use Retin-A.

Since it was such a new product, and skincare technology was so much more basic in the early ’90s, I couldn’t develop a home care plan to use along with the cream to lessen the side effects. After constant dryness, clients using Retin- A simply gave up, because they couldn’t tolerate how bad their skin looked—an effect that was the exact opposite of what they had hoped. So much for that.

However, I remained a firm believer in the power of Retin-A to reduce wrinkles. I saw what it did to Dr. Fitzpatrick’s hand, and I would never forget it. I had a few clients who stuck it out, and after three to five months or so of use, the side effects lessened and the anti-aging, skin-smoothing, wrinkle-reducing benefits kicked in. Sure, they had to be careful when out in the sun, but the side effects would become manageable. In fact, I had one client named Madeline who stayed with it, and every time I saw her, her wrinkles were diminished.

I wouldn’t necessarily encourage my clients to get the prescription for Retin-A, because it takes effort and commitment to get the true benefits, and most clients simply didn’t have the patience. However, if a client asked me about it, I would encourage them to try it (after consulting with their doctor, of course). Then, I would develop a home care plan to give their skin the best result.

Read: The Beginners Guide to Using Retinol

When I turned 35 and my own signs of aging were appearing, I decided it was time to try Retin-A myself, so I visited a dermatologist colleague of mine for a prescription. Unfortunately, I soon discovered that it didn’t agree with my skin. Although I introduced it slowly, and used it sparingly, I developed eczema on my eyelids a week after starting it (even though I never even used it on that area.) The reason for this is that Retinoic Acid (the FDA-approved active ingredient in Retin-A, Renova, and Tazorac) works within the entire skin—not just on a surface level—so it would stimulate a breakdown in my skin’s lipid barrier on the thinnest area of my face (my eyelids) and cause irritation.

Aside from the eczema, I do recall one other peculiar thing that would happen the few times I used it a night.  I would wake up in the morning and feel what I can only describe as a little heartbeat in my face—almost like a little pulsing sensation. I knew this meant that something was occurring within the skin (almost as though I could feel my collagen being stimulated?). I’m not sure what it was, but I could feel it “working.” Ultimately, I decided to discontinue it, due to the eczema.

Non-Prescription Options:

In the early 2000s, cosmetic companies started introducing non-prescription retinol products. They were were marketed as a way to reap the results of the prescription versions, without the side effects. My chemists had access to these ingredients, so I played around with developing a formula, yet I just never felt that the formulas I came up with would get the same results as the stronger prescription form. I decided to wait until new technology presented more effective options.

Finally, a few years ago, I created what I consider to be the perfect retinol serum. When I was testing the new formula, I applied it at night, and much to my surprise, I could feel the pulsating sensation in my skin when I woke the following morning—the same one I experienced when using Retin-A! Wow. This was it. I was now convinced that I could get prescription-strength results with an over-the-counter product.

Since then, I’ve been using the formula consistently, and I’m happy to report that I’m extremely impressed with the skin-smoothing results. My pores appear smaller, my brown spots have lessened, and my lines and wrinkles have truly softened. What’s more is that I haven’t experienced any extreme sensitivity (or eczema!). I get more compliments on my skin than ever.

Here’s what I know for sure about retinol: when it’s used LONG TERM, along with exfoliating products to enhance the absorption of this active ingredient, you can get beautiful results.

Note: There is no instant gratification when it comes to using a retinol product (even the prescription form) like there is with an acid-based product. Also, you may not experience the pulsating sensation in the skin like I do. Finally, it can take at least two months to see visible results, but trust me, if you use this product long term, your skin will look younger.

Read: Three Facial Features That Will Guarantee You’ll Look Younger Longer

Disclaimer: Content found on and, including text, images, audio, or other formats were created for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website or blog.


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  1. Is there a way to get a sample of this product? Two retinol creams have caused me have have an eczema flare up and I don’t want to buy another bottle if this turns out the same way.

    Posted By: Emily A  | 

    • Hi Emily, Unfortunately, we don’t have a sample size of this. As you may have seen in my video, I have personally always had an issue with vitamin A bringing out eczema for me and I feel confident that your skin would do really well with this formula. But we do have a 45-day return policy.

      Posted By: Renée Rouleau  | 

  2. Hi if I stop using retinols will all my agespots, sunspots come back. I dont ever tan or spend long hours in the sun.

    Posted By: Nix  | 

    • Hard to say but they could, simply because with age and hormones, brown spots rise to the surface.

      Posted By: Renée Rouleau  | 

  3. Hi, what is ur return n exchange policy

    Posted By: Rajvir  | 

  4. Hi Renee,
    I am 21 years old and have been on a retinoid for almost 10 months now. I was wondering…is my skin less likely to get badly burned from the sun now that I’ve been on it for a longer period of time? Also, will their be any bad side effects if I continue using this for many years?
    Thanks 🙂

    Posted By: Meg  | 

    • I’m assuming you’re referring to a prescription retinoid, not a gentler retinol product? Yes, it will make the skin more sun sensitive but if you’re good about applying sunscreen generously and wearing it daily, you should be okay. If you’re going to the beach or will spending time outdoors, I would suggest you stop using it a week in advance. As for bad side effects, I don’t know your skin personally but it can make it thinner with continued use so it can make your skin more transparent and sensitive. But the good news is, it will definitely help prevent wrinkles. Long term retinoid use is not harmful. If your skin gets sensitive, you may want to cut back on using it a little.

      Posted By: Renée Rouleau  | 

  5. Is this product still coming out in October? Looking forward to trying it.

    Posted By: Tracy  | 

    • Hi Tracy, It will be coming out in November. Good things come to those who wait. It will be here soon. 🙂

      Posted By: Renée Rouleau  | 

  6. Oh!! Just when I was considering using retinol based products again. But the last time I used an OCD retinol product, after a year my face turned more red and sensitive then ever. I used to not have problems with acne scarring, but after one year of using the product, my scars just won’t go away now.

    I currently use Vitamin C day and night, as suggested by my dermatologist. It has been nearly a year and a half since I started. Should I try using retinol products at night? I am currently 25 years, and wondering if I should start an anti-aging regime.

    Posted By: Elizabeth  | 

    • Hi Elizabeth,
      All retinol products are different so just because you didn’t agree with that formula doesn’t mean you can’t ever use it again. When using retinol, be sure your vitamin C serum is a stable, no-sting formula so as not to irritate the skin. I find that people who use both retinol and the sensitizing form of vitamin C, can get redness over time. My Vitamin C&E Treatment is really gentle, but super effective. See it here. But yes, you should definitely use a retinol product. Mine should be out in November.

      Posted By: Renée Rouleau  | 

  7. I’m really looking forward to using this. 🙂
    Do you use this serum every night or do you alternate it with an AHA and hydrating serum? Also, how long did dryness persist when you started it? (I have oily skin that tends to get dehydrated easily and retinols/retinoids kinda scare me lol)

    Posted By: Ashly  | 

    • You would alternate it with an AHA or BHA serum and regular anti-aging serum for your skin type. I didn’t have much dryness at all. It’s going to be perfect for you. Stay tuned! Renee

      Posted By: Renée Rouleau  | 


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